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Werner Arber

Werner Arber
Werner Arber Born June 3, 1929
Nationality SwitzerlandFields microbiologyKnown for restriction endonucleasesNotable awards 1978, Nobel Prize in Physiology or Medicine

Werner Arber (born June 3, 1929) is a Swiss microbiologist and geneticist. Along with American researchers Hamilton Smith and Daniel Nathans, Werner Arber shared the 1978 Nobel Prize in Physiology or Medicine for the discovery of restriction endonucleases. Their work would lead to the development of recombinant DNA technology.

Werner Arber studied chemistry and physics at the Swiss Federal Institute of Technology in Zürich from 1949 to 1953. Late in 1953 he took an assistantship for electron microscopy at the University of Geneva, in time left the electron microscope, went on to research bacteriophages and write his dissertation on defective lambda prophage mutants. He received his doctorate in 1958 from the University of Geneva.

Arber then worked at the University of Southern California in phage genetics with Joe Bertani starting in the summer of 1958. Late in 1959 he accepted an offer to return to Geneva at the beginning of 1960, but only after spending "several very fruitful weeks"[1] at each of the laboratories of Gunther Stent at University of California, Berkeley, Joshua Lederberg at Stanford University and Salvador Luria at the Massachusetts Institute of Technology.

Back at the University of Geneva, he worked in a laboratory in the basement of the Physics Institute where he carried out productive research and hosted "a number of first class graduate students, postdoctoral fellows and senior scientists."[2] In 1965 he was promoted to extraordinary professor for molecular genetics at the University of Geneva. In 1971 he moved to the University of Basel, after spending a year as a visiting professor in the Department of Molecular Biology of the University of California in Berkeley. In Basel, he was one of the first persons to work in the newly constructed Biozentrum [3], which housed the departments of biophysics, biochemistry, microbiology, structural biology, cell biology and pharmacology which was conducive to interdisciplinary research.

He is member of the World Knowledge Dialogue Scientific Board.

Arber is married and has two daughters.

References

• Konforti, B (2000), “History. The servant with the scissors.”, Nat. Struct. Biol. 7 (2): 99-100, 2000 Feb, PMID:10655607, doi:10.1038/72469, <http://www.ncbi.nlm.nih.gov/pubmed/10655607> 
• Raju, T N (1999), “The Nobel chronicles. 1978: Werner Arber (b 1929); Hamilton O Smith (b 1931); Daniel Nathans (b 1928).”, Lancet 354 (9189): 1567, 1999 Oct 30, PMID:10551539, <http://www.ncbi.nlm.nih.gov/pubmed/10551539> 
• Shampo, M A & Kyle, R A (1995), “Werner Arber--Nobel laureate.”, Mayo Clin. Proc. 70 (10): 945, 1995 Oct, PMID:7564545, <http://www.ncbi.nlm.nih.gov/pubmed/7564545> 
• Kroon, A M (1979), “[The Nobel Prize for Medicine and Physiology in 1978 (Werner Arber, Daniel Nathans, Hamilton Smith)]”, Nederlands tijdschrift voor geneeskunde 123 (5): 153-6, 1979 Feb 3, PMID:368662, <http://www.ncbi.nlm.nih.gov/pubmed/368662> 
• Piekarowicz, A (1979), “[Werner Arber, Daniel Nathans and Hamilton Smith. Nobel prizes for the studies on DNA restriction enzymes]”, Postepy Biochem. 25 (2): 251-3, 1979, PMID:388391, <http://www.ncbi.nlm.nih.gov/pubmed/388391> 
• Berg, K (1978), “[The Nobel prize in physiology and medicine 1978. Nobel prize to a controversial research field]”, Tidsskr. Nor. Laegeforen. 98 (34-36): 1741-2, 1978 Dec 10, PMID:725894, <http://www.ncbi.nlm.nih.gov/pubmed/725894> 
• Desiderio, S & Boyer, S (1978), “Arber, Smith and Nathans: Nobel Laureates in medicine and physiology, 1978.”, The Johns Hopkins medical journal 143 (5): ix-x, 1978 Nov, PMID:364154, <http://www.ncbi.nlm.nih.gov/pubmed/364154> 
• “The Nobel prizewinners 1978: medicine. From modest beginnings...”, Nature 275 (5682): 689-90, 1978, 1978 Oct 26, PMID:360075, <http://www.ncbi.nlm.nih.gov/pubmed/360075> 
• Lagerkvist, U (1978), “[To split a gene]”, Lakartidningen 75 (43): 3892-4, 1978 Oct 25, PMID:279742, <http://www.ncbi.nlm.nih.gov/pubmed/279742> 
• Petterson, R (1978), “[Nobel prize laureates in physiology and medicine]”, Duodecim; lääketieteellinen aikakauskirja 94 (23): 1466-9, 1978, PMID:729493, <http://www.ncbi.nlm.nih.gov/pubmed/729493> 

External links

• Autobiography for the Nobel Prize in Physiology or Medicine 1978
• Free to View Video Interview with Werner Arber provided by the Vega Science Trust.

v • d • eNobel Laureatesin Physiology or Medicine

Baruch Blumberg / Daniel Gajdusek (1976) · Roger Guillemin / Andrew V. Schally / Rosalyn Yalow (1977) · Werner Arber / Daniel Nathans / Hamilton O. Smith (1978) · Allan Cormack / Godfrey Hounsfield (1979) · Baruj Benacerraf / Jean Dausset / George Snell (1980) · Roger Sperry / David H. Hubel / Torsten Wiesel (1981) · Sune Bergström / Bengt I. Samuelsson / John Vane (1982) · Barbara McClintock (1983) · Niels Jerne / Georges Köhler / César Milstein (1984) · Michael Brown / Joseph L. Goldstein (1985) · Stanley Cohen / Rita Levi-Montalcini (1986) · Susumu Tonegawa (1987) · James W. Black / Gertrude B. Elion / George H. Hitchings (1988) · J. Michael Bishop / Harold E. Varmus (1989) · Joseph Murray / E. Donnall Thomas (1990) · Erwin Neher / Bert Sakmann (1991) · Edmond Fischer / Edwin G. Krebs (1992) · Richard J. Roberts / Phillip Sharp (1993) · Alfred G. Gilman / Martin Rodbell (1994) · Edward B. Lewis / Christiane Nüsslein-Volhard / Eric F. Wieschaus (1995) · Peter C. Doherty / Rolf M. Zinkernagel (1996) · Stanley B. Prusiner (1997) · Robert F. Furchgott / Louis Ignarro / Ferid Murad (1998) · Günter Blobel (1999) · Arvid Carlsson / Paul Greengard / Eric Kandel (2000)

Complete roster · 1901–1925 · 1926–1950 · 1951–1975 · 1976–2000 · 2001–present Categories: Swiss microbiologists | Members of the National Academy of Sciences | Swiss biologists | Phage workers | Nobel laureates in Physiology or Medicine | Swiss Nobel laureates | Members of the Pontifical Academy of Sciences | ETH Zurich alumni | Inductees of the Brazilian Order of Scientific Merit | People from Aargau | 1929 births | Living people

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