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Edward B. Lewis

For other persons of the same name, see Edward Lewis. Edward B. Lewis
Edward B. Lewis Born May 20, 1918
Wilkes-Barre, PennsylvaniaDied July 21, 2004
Nationality AmericanFields geneticsAlma materCalifornia Institute of TechnologyDoctoraladvisor Alfred SturtevantKnown for Research into genetics of the common fruit flyNotable awards 1995Nobel Prize in Medicine

Edward B. Lewis (May 20, 1918 – July 21, 2004) was an American geneticist, the winner of the 1995 Nobel Prize in Medicine.

Lewis was born in Wilkes-Barre, Pennsylvania and graduated from E.L. Meyers High School. He received a BA in Biostatistics from the University of Minnesota in 1939, where he worked on Drosophila melanogaster in the lab of C.P. Oliver. In 1942 Lewis received a Ph.D. from California Institute of Technology (Caltech), working under the guidance of Alfred Sturtevant. After serving as a meteorologist in the U.S. Air Force in World War II, Lewis joined the Caltech faculty in 1946 as an instructor. In 1956 he was appointed Professor of Biology, and in 1966 the Thomas Hunt Morgan Professor of Biology. Among his many awards were the Thomas Hunt Morgan Medal (1983), the Gairdner Foundation International award (1987), the Wolf Foundation prize in medicine (1989), the Rosenstiel award (1990), the National Medal of Science (1990), the Albert Lasker Award for Basic Medical Research (1991), and the Louisa Gross Horwitz Prize (1992).

His Nobel Prize winning studies with Drosophila founded the field of developmental genetics and laid the groundwork for our current understanding of the universal, evolutionarily conserved strategies controlling animal development. He is credited with development of the complementation test. His key publications in the fields of genetics, developmental biology, radiation and cancer are presented in the book Genes, Development and Cancer, which was released in 2004.

References

• Crow, James F & Bender, Welcome (2004), “Edward B. Lewis, 1918-2004.”, Genetics 168 (4): 1773-83, 2004 Dec, PMID:15611154, <http://www.ncbi.nlm.nih.gov/pubmed/15611154> 
• Duncan, Ian & Celniker, Susan E (2004), “In memoriam: Edward B. Lewis (1918-2004).”, Dev. Cell 7 (4): 487-9, 2004 Oct, PMID:15469837, doi:10.1016/j.devcel.2004.09.005, <http://www.ncbi.nlm.nih.gov/pubmed/15469837> 
• Mishra, Rakesh K (2004), “Edward B Lewis (1918-2004).”, J. Biosci. 29 (3): 231-3, 2004 Sep, PMID:15381844, <http://www.ncbi.nlm.nih.gov/pubmed/15381844> 
• Winchester, Guil (2004), “Edward B. Lewis 1918-2004.”, Curr. Biol. 14 (18): R740-2, 2004 Sep 21, PMID:15380080, doi:10.1016/j.cub.2004.09.007, <http://www.ncbi.nlm.nih.gov/pubmed/15380080> 
• Scott, Matthew P & Lawrence, Peter A (2004), “Obituary: Edward B. Lewis (1918-2004).”, Nature 431 (7005): 143, 2004 Sep 9, PMID:15356617, doi:10.1038/431143a, <http://www.ncbi.nlm.nih.gov/pubmed/15356617> 
• Tannen, Terrell, “Edward B. Lewis.”, Lancet 364 (9435): 658, PMID:15341018, doi:10.1016/S0140-6736(04)16878-5, <http://www.ncbi.nlm.nih.gov/pubmed/15341018> 
• Raju, T N (2000), “The Nobel chronicles. 1995: Edward B Lewis (b 1918), Christiane Nüsslein-Volhard (b 1942), and Eric Francis Wieschaus (b 1947).”, Lancet 356 (9223): 81, 2000 Jul 1, PMID:10892797, <http://www.ncbi.nlm.nih.gov/pubmed/10892797> 
• Vennström, B & Lagerkrantz, H (1995), “[The 1995 Nobel Prize in medicine or physiology--awarded Edward B. Lewis, Christiane Nusslein-Volhard and Eric Wieschaus]”, Ugeskr. Laeg. 157 (50): 6999-702, 1995 Dec 11, PMID:8545917, <http://www.ncbi.nlm.nih.gov/pubmed/8545917> 
• Etcheverry, G J (1995), “[Nobel prize of physiology or medicine 1955: Edward B. Lewis, Christiane Nüsslein-Volhard, Eric Wieschaüs. The flies and the keys of the embryonic development]”, Medicina (B Aires) 55 (6): 715-7, 1995, PMID:8731586, <http://www.ncbi.nlm.nih.gov/pubmed/8731586> 

See also

• Transvection (genetics)

External links

• Caltech obituary
• The Official Site of Louisa Gross Horwitz Prize

v • d • eNobel Laureatesin Physiology or Medicine

Baruch Blumberg / Daniel Gajdusek (1976) · Roger Guillemin / Andrew V. Schally / Rosalyn Yalow (1977) · Werner Arber / Daniel Nathans / Hamilton O. Smith (1978) · Allan Cormack / Godfrey Hounsfield (1979) · Baruj Benacerraf / Jean Dausset / George Snell (1980) · Roger Sperry / David H. Hubel / Torsten Wiesel (1981) · Sune Bergström / Bengt I. Samuelsson / John Vane (1982) · Barbara McClintock (1983) · Niels Jerne / Georges Köhler / César Milstein (1984) · Michael Brown / Joseph L. Goldstein (1985) · Stanley Cohen / Rita Levi-Montalcini (1986) · Susumu Tonegawa (1987) · James W. Black / Gertrude B. Elion / George H. Hitchings (1988) · J. Michael Bishop / Harold E. Varmus (1989) · Joseph Murray / E. Donnall Thomas (1990) · Erwin Neher / Bert Sakmann (1991) · Edmond Fischer / Edwin G. Krebs (1992) · Richard J. Roberts / Phillip Sharp (1993) · Alfred G. Gilman / Martin Rodbell (1994) · Edward B. Lewis / Christiane Nüsslein-Volhard / Eric F. Wieschaus (1995) · Peter C. Doherty / Rolf M. Zinkernagel (1996) · Stanley B. Prusiner (1997) · Robert F. Furchgott / Louis Ignarro / Ferid Murad (1998) · Günter Blobel (1999) · Arvid Carlsson / Paul Greengard / Eric Kandel (2000)

Complete roster · 1901–1925 · 1926–1950 · 1951–1975 · 1976–2000 · 2001–present v • d • eWolf Prize in Medicine Laureates

George Snell / Jean Dausset / Jon J. van Rood (1978) · Roger Sperry / Arvid Carlsson / Oleh Hornykiewicz (1979) · César Milstein / Leo Sachs / James L. Gowans (1980) · Barbara McClintock / Stanley Norman Cohen (1981) · Jean-Pierre Changeux / Solomon H. Snyder / James W. Black (1982) · Donald F. Steiner (1984/5) · Osamu Hayaishi (1986) · Pedro Cuatrecasas / Meir Wilchek (1987) · Henri G. Hers / Elizabeth F. Neufeld (1988) · John Gurdon / Edward B. Lewis (1989) · Maclyn McCarty (1990) · Seymour Benzer (1991) · Judah Folkman (1992) · Michael Berridge / Yasutomi Nishizuka (1994/5) · Stanley B. Prusiner (1995/6) · Mary F. Lyon (1997) · Michael Sela / Ruth Arnon (1998) · Eric Kandel (1999) · Avram Hershko / Alexander Varshavsky (2001) · Ralph L. Brinster / Mario Capecchi / Oliver Smithies (2002/3) · Robert Weinberg / Roger Y. Tsien (2004) · Alexander Levitzki / Anthony R. Hunter / Anthony Pawson (2005) · Howard Cedar / Aharon Razin (2008)

Agriculture · Arts · Chemistry · Mathematics · Medicine · Physics Categories: 1918 births | 2004 deaths | People from the Scranton--Wilkes-Barre metropolitan area | American biologists | American geneticists | Nobel laureates in Physiology or Medicine | Bucknell University alumni | National Medal of Science laureates | California Institute of Technology alumni | University of Minnesota alumni | Wolf Prize in Medicine laureates | People from Wilkes-Barre, Pennsylvania | California Institute of Technology faculty

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