Bubonic plague

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Bubonic plague, when the germs were carried in the bloodstreams of fleas and if the rats were biten by the fleas, then the rats were infected and the plague was passed on. It is the best-known manifestation of the bacterial disease plague, caused by the bacterium Yersinia pestis. Bubonic plague is often used synonymously for plague, but it does in fact refer specifically to an infection that enters through the skin and travels through the lymphatics, as is often seen in flea-borne infections. Bubonic Plague kills about 70% of patients in 4-7 days.

1 Pathology and transmission
2 Symptoms
3 See also
4 Notes

Pathology and transmission

The Bubonic plague is an infection of the lymphatic system, usually resulting from the bite of an infected flea. The bacteria rapidly spreads to the lymph nodes and multiply. Yersinia pestis can resist phagocytosis and even reproduce inside phagocytes and kill them. As the disease progresses, the lymph nodes can hemorrhage and become necrotic. Bubonic plague can progress to lethal septicemic plague in some cases.

Symptoms

The most famous symptom of bubonic plague are swollen lymph nodes, called buboes. These are commonly found in the armpits, groin or neck. The Bubonic Plague was the first step of the ongoing Plague. The two other forms of the Plague, Pneumonic and Septicemic, resulted after a patient with the Bubonic Plague developed Pneumonia or blood poisoning.